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In this episode, Dr. Brandon & Dr. Morgentaler talk about the off-label use of bremelanotide (Vyleesi/PT-141) in men — its potential benefits for libido/erections, origins, side effects (notably nausea), and how patients often access it via compounding pharmacies.
- 00:05 – What is Bremelanotide: Dr. Brandon & Dr. Morgentaler dive into Bremelanotide and share how the Goldsteins have been pioneering its research.
- 02:08 – Faking Orgasm: They laugh about the iconic Katz’s Deli “When Harry Met Sally” scene and its connection to sexual medicine history.
- 03:06 – How Bremelanotide Works: The doctors explain how Bremelanotide works, how it’s used by both women and men, and why refills tell an important story.
- 08:43 – Addressing Criticism: They tackle the criticism that women take these meds “for men,” pushing back and stressing women’s right to pleasure.
- 19:48 – Wrapping up: They encourage listeners to talk with their doctors or compounding pharmacies if they want to explore this option.
Resources
Goldstein, I., & Goldstein, S. (n.d.). [Abstract on off-label use of Bremelanotide (PT-141) in men: Refill rates and sexual function outcomes]. The Journal of Sexual Medicine.
