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In this episode, Dr. Brandon and Dr. Morgentaler talk about the emerging evidence that testosterone therapy may be safe — and even beneficial — for men with metastatic prostate cancer.
- 00:11 – Testosterone Use in Metastatic Prostate Cancer: Dr. Morgentaler introduces the surprising evidence that testosterone may not be harmful in metastatic prostate cancer, and Dr. Brandon sets the stage for the discussion.
- 00:49 – Historical Perspective on Androgen Deprivation: Dr. Morgentaler explains the 80-year history of lowering testosterone as standard treatment and why its benefits have been overstated.
- 03:59 – Challenging the Norm: Testosterone Treatment Cases: Dr. Morgentaler shares real patients he treated with testosterone — supported by Dr. Brandon — with outcomes that contradict the belief that testosterone accelerates cancer.
- 10:09 – Modified BAT: A New Approach: Dr. Morgentaler describes his “modified BAT” cycling strategy for advanced cancer, while Dr. Brandon reflects on the quality-of-life implications.
- 17:40 – Conclusion and Future Directions: Both Dr. Brandon and Dr. Morgentaler call for new trials and highlight how modern evidence challenges the fear that testosterone fuels cancer.
Resources
TRAVERSE Study Group. (2023). The TRAVERSE randomized controlled trial on testosterone therapy in men.
Morgentaler, A. (2021). Testosterone therapy in men with advanced prostate cancer: A case series analysis.
Morgentaler, A. (2020). Clinical outcomes of continuous testosterone therapy in metastatic prostate cancer: Case report and review.
